| abstract |
The reporter construct contains a mammalian INGAP 5′-regulatory region or fragment thereof, a minimal promoter component or heterologous promoter from the mammalian INGAP, and a reporter gene. This reporter construct may be used alone or in combination to screen for agents that upregulate or downregulate reporter gene expression. Alternatively, this reporter construct can be used to screen for agents that bind to the hamster INGAP 5′-regulatory region or fragment thereof.n n n n Nucleic acid sequences, reporter constructs, nucleotide sequences, INGAP expression, test agents |