| abstract |
The present invention does not contain a complexed protein naturally present in the botulinum neurotoxin complex, and Clostridium ( Clostridium botulinum) botulinum ) and pharmaceutical compositions comprising a botulinum neurotoxin that does not contain a botulinum neurotoxin, or a complexed protein that naturally forms a complex with the botulinum neurotoxin and that is chemically modified or genetically modified. In addition, the pharmaceutical compositions of the present invention are excellent in stability and advantageously formulated without the use of human serum albumin.n n n Botulinum neurotoxin, botulinum neurotoxin complex, complexed protein, modified botulinum neurotoxin |