http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20070026654-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2851ad4adff76730eb7cb7b5d7a0d09a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-401 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C219-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-24 |
| filingDate | 2005-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86ca971b3a1bd1a6b66dd84535528135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d917eeaa1262b2c57ddcfa0d42104184 |
| publicationDate | 2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20070026654-A |
| titleOfInvention | Eye-Selective Drags and Prodrugs |
| abstract | The present invention discloses compounds of the same formula as defined herein, wherein R 1 and R 2 are each independently H, W, or phenoxyl protecting groups; R 4 is H or W, provided that at least one of R 1 , R 2, and R 4 is W; R 3 is hydrogen, straight or branched C 1 -C 10 Alkyl, cycloalkyl, amino, C 1 -C 10 alkoxy, —NHC (= 0) R a or —C (═O) N (H) R a , wherein R a is alkyl, aryl or heterocyclyl; Z is —O—, —O (C═O) — or NH (C═O) —, where Z is —O—, R 5 is straight or branched C 1 -C 10 alkyl, cycloalkyl , Cycloalkyl substituted by one or more straight or branched C 1 -C 10 alkyl, C 1 -C 10 alkoxyalkyl, amino, benzyl, tetrahydrofuranyl, dihydrofuranyl, furanyl, morpholinyl, Piperidinyl, tetrahydropyranyl, dioxolanyl, 2,2-dimethyl dioxolanyl, dioxanyl, pyrrolyl, pyrrolidinyl, tetrahydrooxazolyl, dihydrooxazolyl, phenyl, C 1 -C 10 Phenyl substituted by alkyl, C 1 -C 10 alkoxy or halo; W is the same as defined herein; Each R 6 is independently H, straight or branched C 1 -C 10 alkyl, or straight or branched C 1 -C 10 alkoxyalkyl; R 7 is alkyl, cycloalkyl, aryl or aralkyl; When Z is -O (C = O)-, R 5 is a cyclo substituted by straight or branched C 1 -C 10 alkyl, cycloalkyl, or one or more straight or branched C 1 -C 10 alkyl Alkyl, C 1 -C 10 alkoxyalkyl, amino, benzyl, tetrahydrofuranyl, dihydrofuranyl, furanyl, morpholinyl, piperidinyl, tetrahydropyranyl, dioxolanyl, 2,2-dimethyl diox Solanyl, dioxanyl, pyrrolyl, pyrrolidinyl, tetrahydrooxazolyl, dihydrooxazolyl, phenyl, C 1 -C 10 alkyl, C 1 -C 10 alkoxy or phenyl substituted by halo; W is the same as defined herein; Each R 6 is independently H, straight or branched C 1 -C 10 alkyl, or straight or branched C 1 -C 10 alkoxyalkyl; R 7 is alkyl, cycloalkyl, aryl or aralkyl; When Z is Z is -NH (C = 0)-, R 5 is substituted by straight or branched C 1 -C 10 alkyl, cycloalkyl, or one or more straight or branched C 1 -C 10 alkyl Cycloalkyl, C 1 -C 10 alkoxyalkyl, amino, benzyl, tetrahydrofuranyl, dihydrofuranyl, furanyl, morpholinyl, piperidinyl, tetrahydropyranyl, dioxolanyl, 2,2- Dimethyl dioxolanyl, dioxanyl, pyrrolyl, pyrrolidinyl, tetrahydrooxazolyl, dihydrooxazolyl, phenyl, C 1 -C 10 alkyl, C 1 -C 10 alkoxy or phenyl substituted by halo; W is the same as defined herein; Each R 6 is independently H, straight or branched C 1 -C 10 alkyl, or straight or branched C 1 -C 10 alkoxyalkyl. The present invention also discloses a method of preparing the compound, a pharmaceutical composition containing the compound, and a method of treating a patient by administering the pharmaceutical composition. |
| priorityDate | 2004-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.