| abstract |
The present invention provides a process for the preparation of (3R, 3aS, 6aR) hexahydro-furo [2,3-b] furan-3-ol (6) and other novel intermediates for use in this process, (3aR, 4S, 6aS). ) 4-methoxy-tetrahydro-furo [3,4-b] furan-3-one (4). More specifically, the present invention relates to a process for preparing pure (3R, 3aS, 6aR) hexahydro-furo [2,3-b] furan-3-ol as diastereomer and (3R, 4S, 6aS) 4-meth. Method for crystallization of oxy-tetrahydro-furo [3,4-b] furan-2-one and (3aR, 4R, 6aS) 4-methoxy-tetrahydro-furo [3,4-b] -furan-2- A method for epimerizing with (3aR, 4S, 6aS) 4-methoxy-tetrahydro-furo [3,4-b] furan-2-one of ions: |