http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20070011528-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-26 |
| filingDate | 2005-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb279e9e6f3b27206cdfcb8b9380f5bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3b8016ab1f2fa4bddd6798741347ea8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49d83aeb54cdd26470a4bd291bc5947 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b160629d789c7d2cc85f71ca776decd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37bfba189b20bbfccc4bfba594af8fcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0594c23742091c106eb158ec1988ea8 |
| publicationDate | 2007-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20070011528-A |
| titleOfInvention | Pyrrolidin-2-one and piperidine-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| abstract | Compounds of formula (I), their N-oxide forms, pharmaceutically acceptable addition salts and stereochemically isomeric forms thereof for use as medicaments:n n n n n n n n Wherein n is 1 or 2; L is C 1 - 4 alkyl from 4 alkyl, C 1 - 3 alkyloxy 1 -C 4 alkyl-, hydroxy -C 1 - 4 alkyl, hydroxy, C 1 - 3 alkyloxy-phenyl, or -C 1 by the selected one or two substituents optionally substituted C 1 - 3 alkyl represents a linker; M is a direct bond, or hydroxy, C 1 - 4 alkyl or C 1 - 4 by the one or two substituents selected from alkyloxy, optionally substituted C 1 - 3 alkyl represents a linker; R 1 and R 2 are each independently hydrogen; Halo; Cyano; Hydroxy; The optionally substituted by halo C 1 - 4 alkyl; Hydroxy, Ar 1, and if one can be selected from halo or 2 or a C 1 group optionally substituted by three substituents - wherein - 4 alkyloxy; Or R 1 and R 2 together with the phenyl ring attached thereto form naphthyl or 1,3-benzodioxolyl, wherein said naphthyl or 1,3-benzodioxolyl is optionally substituted by halo and ; R 3 is hydrogen, halo, C 1 -4 alkyl, C 1 - 4 alkyloxy -, cyano or hydroxy represents hydroxy; R 4 is hydrogen, halo, C 1 - 4 alkyl, C 1 - 4 alkyloxy -, cyano, or represents a hydroxyl; R 5 is hydrogen, C 1 - 4 alkyl or Ar 2 -C 1 - represents a 4-alkyl; R 6 is hydrogen, halo, C 1 - 4 alkyl or C 1 - represents a-4 alkyloxy; Ar 1 and Ar 2 represents a phenyl or naphthyl, each independently, wherein the phenyl and naphthyl are C 1 - may optionally be substituted by a 4-alkyl-4-alkyl, C 1 - 4 alkyl-oxy-phenyl, or -C 1 . |
| priorityDate | 2004-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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