http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20070011354-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36acffd633dba9a2522c571072334527 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2005-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_056ea58830465103fae3dbcc1c7947db |
publicationDate | 2007-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20070011354-A |
titleOfInvention | Methods of detecting STRPs such as fragile mucosal syndrome |
abstract | A method for detecting short repeat polymorphisms (STRPs), such as fragile X chromosome syndrome, comprising PCR to amplify a nucleic acid located along a chromosome in genomic DNA that includes all of the STRs and substantially contiguous fragments of nucleic acid adjacent to the STRs. This is used. Thereafter, a single-stranded product is obtained, and (i) colorimetrically labeled oligonucleotides targeting STRs and (ii) adjacent DNA fragments are matched with these single-stranded products, which are then bound to the solid phase and remain Separated from the target material. The labeled oligonucleotide target material is recovered by treatment with a base, which is then matched to a microarray having a plurality of points containing appropriate oligonucleotide probes complementary thereto. Following matching, the colorimetric intensity of the matched, labeled target material at a particular point on the microarray is measured to obtain individual values that are compared to the results of known control samples, thereby determining the STRs in the site of the DNA of interest to be analyzed. Accurately quantify the number. |
priorityDate | 2004-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.