| abstract |
A liposome formulation with excellent storage stability that can stably support a drug that impairs stability under acidity without impairing effects such as blood stability due to membrane modification by a hydrophilic polymer, and a lipid double containing phospholipid as a main membrane material. A single lamellae vesicle formed into a membrane and an aqueous phase having a pH of 5 or less present in the vesicles, wherein the vesicles carry a drug, wherein the vesicles provide a liposome formulation in which only its outer surface is modified with a hydrophilic polymer. |