http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20070002028-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7a3886f1cdaa7211491a8f2de9831c4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0652 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
filingDate | 2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9c2119403bfa903c407e9cf99d143f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caeb401c2f22a17845a258ca38af1e39 |
publicationDate | 2007-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20070002028-A |
titleOfInvention | Tissue-like tissues and macroscopic tissue-like structures produced by macromass culture of cells, and macromass culture methods |
abstract | Three-dimensional tissue-like tissue of cells by high cell-seed-density of the term macromass culture is described. By macromass culture, cells can be made to structure them in tissue-like form without the help of scaffolds and three-dimensional macroscopic tissue-like structures can be made entirely from the cells. Tissue-like tissues and macroscopic tissue-like structures can be generated (at least) from fibroblasts of mesenchymal origin, which can be differentiated cells or multipotent adult stem cells. In this work, tissue-like tissues and macroscopic tissue-like structures were generated from skin fibroblasts, adipose stromal cell-derived osteogenic cells, chondrocytes, and osteoblasts. Factors that lead to macroscopic tissue formation are large scale cultures at high cell seeding densities per unit area or three dimensional space, ie large scale macromass cultures. No scaffolds or foreign matrices are used to generate tissue, and the tissue is entirely of cellular origin. No other agents (except for high cell-seed-density) that aid in tissue formation, such as tissue-derived chemicals, tissue-induced growth factors, bottoms with special properties, rotational culture, etc., are employed for tissue formation. These tissue-like materials have the potential for use as tissue replacements in the human body. Tissue-like tissues with high cell-seed-densities may also be produced at the microscopic level. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019505346-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101041914-B1 |
priorityDate | 2006-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 212.