| abstract |
In the present invention, the following configurations are disclosed.n n n 1. A fractionation apparatus using a membrane having a filtration section, a concentrating section, a recovering section, and a liquid feeding pump, wherein the circuit including a flow path connecting the filtration section, the concentrating section, and the recovering section is a closed circuit.n n n 2. Antibody adsorption membrane incorporating antibody adsorbing specific protein in the middle or second half of membrane separation system where permeation ratio between human α 1 microglobulin and human albumin is 1.5 or more and 1000 or less without protein adsorbing protein A separation method of a biological component, comprising supplying a sample derived from the biological component to a separation system and separating a part of the biological component.n n n 3. A method of contacting a hollow fiber membrane with a solution containing a plurality of proteins and water, and fractionating the protein, wherein the solution in the fraction contains an organic solvent. |