| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f84747e8d08b1023763356d0e7d1db68 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate |
2004-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4ddf58cf4d95cff3429a31f35561ecd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b441b42e4d2d0f538da861792ff304d |
| publicationDate |
2006-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20060134952-A |
| titleOfInvention |
How to load drugs in liposomes |
| abstract |
The present invention discloses liposome compositions having therapeutic agents protonable in the form of salts with glucuronic anion. The present invention also discloses a process for preparing the composition using an ammonium ion dura mater gradient with glucuronic acid ions as the counterion. In one embodiment where the protonable agent is doxorubicin, the method of the invention is comparable to loading efficiency, faster release without compromising therapeutic efficacy when compared to loading with an ammonium ion gradient with sulfate ions as the counterion. Have speed. |
| priorityDate |
2003-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |