abstract |
The present invention provides a nitrogen-containing condensation represented by the following general formula (I), which expresses human SGLT activity inhibitory action and is useful as a prophylactic or therapeutic agent for diseases caused by hyperglycemia such as diabetes, postprandial hyperglycemia, abnormal glucose tolerance, diabetic complications, obesity, and the like. Ring derivatives or pharmacologically acceptable salts thereof, or prodrugs thereof, wherein R 1 is H, a substitutable alkyl group, an alkenyl group, or the like; R 2 is H, a halogen atom or an alkyl group; R 3 and R 4 are H, OH, a halogen atom, a substitutable alkyl group, etc .; Y is CH or N; Q is alkylene, alkenylene and the like; Ring (A) is an aryl group or heteroaryl group; G is represented by the following general formula (G-1) or a group represented by (G-2) (for formula, E 1 is H, F, OH; E 2 is H, F, methyl, etc.)], and a medicinal composition containing it, And medicinal uses thereof. |