| abstract |
For example, a drug containing a compound represented by the following formula (1) as an active ingredient and having a high affinity for a benzodiazepine ω 3 receptor having a therapeutic and prophylactic effect against anxiety and depression:n n n n n n n n In the formula, R 1 and R 2 independently represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, or the like; R 3 and R 4 independently represent a hydrogen atom, an optionally substituted alkyl group, or the like; R 5 , R 6 , R 7 And R 8 independently represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted aryl group, or the like; X represents an oxygen atom, a sulfur atom, NR 10 or the like (wherein R 10 represents a hydrogen atom, an optionally substituted alkyl group, or the like). |