Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae84948901b77f34fd51c41264d8d19c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2005-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d15740e6dd937e6e3dff40bca5fb7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf825d66414f34bd8a4a19afb53c0089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_697c457f052c9fce2ca49f32e8cd6e7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e50574816e4bc2ae536d3ed1d2c60c7f |
publicationDate |
2006-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20060123541-A |
titleOfInvention |
Neutral Endopeptidase (NEP) and Human Soluble Endopeptidase (hSEP) Inhibitors for the Prevention and Treatment of Neurodegenerative Diseases |
abstract |
The present invention relates to known benzazine, benzoxazepine, benzothiazepine-N-acetic acid and phosphono-substituted with neutral endopeptidase (NEP) and / or human soluble endopeptidase (hSEP) inhibitory activity. A novel use of benzazepineone derivatives. The compounds of the present invention are useful for the preparation of pharmaceutical compositions for the prevention and treatment of neurodegenerative diseases. Compounds of the invention are known from EP 0 733 642 and EP 0 916 679 and can be represented by the formula (1).n n n Formula 1n n n n n n n n In Formula 1, the symbols are as defined in the present specification. |
priorityDate |
2004-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |