| abstract |
Treatment of hyperlipidemia or arteriosclerosis using a composition containing the following components (A) and (B), or treatment of hyperlipidemia or arteriosclerosis by co-administration of the following components (A) and (B), is a conventional therapeutic It is also effective in patients whose cholesterol levels could not be sufficiently lowered to target therapeutic levels, especially those with coronary heart disease:n n n (A) 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor or salt thereof and / or egestimib or prodrug or salt thereof, andn n n (B) a compound represented by the following formula (1) or a salt thereof:n n n n n n n n [Wherein, Ring A represents a substituted or unsubstituted pyridine ring; Y represents a substituted or unsubstituted aromatic group or the like; R 1 represents a hydrogen atom, a substituted or unsubstituted alkyl group, or the like; R 2 represents a hydrogen atom or a lower alkyl group; R 3 represents a lower alkyl group; Z represents a hydroxyl group, an amino group, etc.]. |