| abstract |
It is not a problem in everyday meals, can be taken orally in the long-term or directly, and also gives bones the effect of promoting bone formation and inhibiting bone resorption directly, and can be expected to prevent or improve treatment of various bone diseases. Provided are novel bone formation promoting and / or bone absorption inhibitors, and moreover, food, beverage, medicine or feed for promoting bone formation and / or inhibiting bone absorption. β 2 microglobulin, histone, complement third component, monocyte chemotactic protein 1, lysozyme, ribonuclease, prothrombin, cytochrome P-450, plasminogen, transferrin, thrombin, plasmin, complement fourth component, β diphene At least one of the gods and their enzymatic degradation products is an active ingredient. These substances have an effect of remarkably inhibiting bone resorption by osteoclasts and / or promoting bone growth by promoting the proliferation and differentiation of osteoblasts. |