abstract |
A spray-dried powder composition and method for preparing the same, comprising a group of proteins or analogs thereof for the treatment and prevention of microbial infectious diseases suitable for inhalation into the respiratory tract or for direct delivery to other epidermal cells. Spray-dried powder composition of the present invention is characterized in that it comprises a collectin protein or an analog thereof as an active ingredient and has a particle size of 0.1 to 10 ㎛. The spray-dried powder composition prepared by the production method of the present invention has an effect of suppressing infections of viruses, bacteria, fungi, and the like, and is formulated in a form suitable for inhalation, thereby preventing and / or preventing respiratory infections or trauma by these microorganisms. It is formulated in a form that can supply the active ingredient directly to the site of infection or infectious site as a therapeutic agent. Spray dried powder compositions of the present invention can also be used to prepare tablet formulations by mixing with other excipients.n n n n Mannose-bound lectin, spray drying, preparation method, collectin protein |