| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39c68430bcb778feae2ad4e9640ad0ca |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-314 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18 |
| filingDate |
2004-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb954caae11d655f496cb0a3fcc8ea0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5073ee35383c85dcba1381809ee2b7e9 |
| publicationDate |
2006-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20060056978-A |
| titleOfInvention |
Oligonucleotide Analogues and Methods for Treating Flavivirus Infections |
| abstract |
Methods of inhibiting the replication of flaviviruses in mammalian cells, and oligonucleotide compounds for use in the methods are described. Oligonucleotide analogues (i) have a nuclease resistant backbone, (ii) can be ingested by cells, (iii) contain 8-40 nucleotide bases, and (iv) SEQ ID NOS: 1-4 Have at least 8 base sequences complementary to the virus positive strand RNA genomic region comprising at least a portion. Exposure to the analogs of cells infected with flaviviruses is effective within the cells, the analogs are heteroduplex structures composed of viral ssRNAs and oligonucleotides, have a dissociation temperature (Tm) of at least 45 ° C., virus 5 ′ and Characterized by having base pairs broken between the 3 'cyclized sequences. |
| priorityDate |
2003-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |