abstract |
A leukotriene A4 hydrolase (LTA4H) inhibitor of formula (I), a composition containing the same, and an inhibitory use of LTA4H enzyme activity, and the treatment, inhibition or prevention of inflammation and / or diseases associated with inflammation, wherein X is NR5, O And S and R 5 is one of H or CH 3; Y is selected from the group consisting of CH 2 and O; R 4 is selected from the group consisting of H, OCH 3, Cl, F, Br, I, OH, NH 2, CN, CF 3. |