abstract |
Compound represented by the following formula [I]:n n n n n n n n [Wherein, Ring A and Ring B each represent an optionally substituted benzene ring; Ring C represents an optionally further substituted aromatic ring; R 1 represents a lower alkyl group optionally substituted with optionally substituted hydroxy; X 1a represents a bond or an optionally substituted lower alkylene; X 1b represents a bond or an optionally substituted lower alkylene; X 2 represents a bond, -O- or -S-; X 3 represents a bond or an optionally substituted divalent hydrocarbon group; Y represents any esterified or amidated carboxy], or a salt thereof. Compounds of formula [I] have safer and more potent lipid lowering actions, such as squalene synthase inhibitory action (cholesterol lowering action) and triglyceride lowering action. The compound is useful, for example, as a medicament for preventing or treating hyperlipidemia. |