abstract |
The present invention relates to oral multiparticulate pharmaceutical dosage forms containing pellets, which pellets are 50 to 2500 μm in size and are a) embedded in a matrix of mucoadhesive polymers, including derivatives or conjugates thereof , An inner matrix layer comprising the active ingredient, which is a peptide or a protein, and b) an outer film coating consisting essentially of an anionic polymer or copolymer, which may optionally be formulated as a pharmaceutical adjuvant, in particular an emollient. . |