abstract |
The present invention relates to the use of a novel pyrimidine derivative of formula (I), for the manufacture of a medicament for the treatment or prophylaxis of diseases in response to inhibition of FAK and / or ALK and / or ZAP-70 and / or IGF-IR will be:n n n <Formula I>n n n n n n n n In the formula,n n n R is C 6 - 10 aryl, C 5 - 10 heteroaryl, C 3 - is selected from heterocycloalkyl 10 - 12 cycloalkyl and C 3; n n n R 0 -R 6 are as defined in the specification. |