| abstract |
The present invention relates to compounds of formula (I) wherein R 0 , R 1 , R 2 , Q, V, G and M are as defined in the claims. Compounds of formula (I) are valuable pharmacologically active compounds. The compounds of formula (I) exhibit potent antithrombotic effects and are suitable for the treatment and prophylaxis of cardiovascular diseases such as, for example, thromboembolic diseases or restenosis. Compounds of formula (I) are reversible inhibitors of blood coagulation enzyme factor Xa ("FXa") and / or factor VIIa ("FVIIa"), and generally have a condition or factor in which undesired activity of factor Xa and / or factor VIIa is present Inhibition of Xa and / or factor VIIa can be used in the therapeutic or prophylactic methods that are attempted. The invention also relates to a process for the preparation of compounds of formula (I), in particular their use as active ingredients in the pharmaceutical art, and pharmaceutical preparations comprising the same. |