| abstract |
The present invention relates to a reaction system containing N-acetylglucosamine (GlcNAc), pyruvic acid and cytidine 5'-monophosphoric acid (CMP), and to yeast cells, N-acetylglucosamine-6-phosphate 2-epimerase (GlcNAc-6P 2). CMP-N-acetylnuclear, characterized in that by addition of epimerase), N-acetylneuraminic acid lyase (NeuAc lyase) and CMP-N-acetylneuraminic acid synthase (CMP-NeuAc synthase) It relates to a process for producing laminic acid (CMP-NeuAc).n n n The present invention also relates to a reaction system containing N-acetylglucosamine (GlcNAc) and cytidine 5'-monophosphate (CMP), which is a yeast cell and N-acetylglucosamine-6-phosphate 2-epimerase (GlcNAc-6P 2-). Epimerase), N-acetylneuraminic acid synthase (NeuAc synthase) and CMP-N-acetylneuraminic acid synthase (CMP-NeuAc synthase). It relates to a method for producing acetylneuraminic acid (CMP-NeuAc). |