| abstract |
The present invention is a compound of formula (I); It relates to base, acid addition salt, hydrate or solvate thereof.n n n <Formula I>n n n n n n n n In the formula: A = N or CR 2 ; R 2 = H, F, OH , CN, CF 3, C 1 -6 - alkyl, C 1 -6 - alkoxy; N = 2 or 3 and m = 2 when A = N; When A is CR 2 n = 1, 2 or 3 and m = 1 or 2; B = covalent bond or a C 1 -8 - alkylene; R 1 = optionally substituted heteroaryl; R 3 = CHR 4 CONHR 5 ; R 4 = H or C 1 -6 - alkyl; R 5 = H, C 1 -6 - alkyl, C 3 -7 - cycloalkyl, C 3 -7 - cycloalkyl, -C 1 -6 - is alkylene.n n n The invention also relates to its therapeutic use. |