abstract |
Formula (I) having an insulin secretagogue action according to the present inventionn n n n n n n n {In formula, R < 1> represents a hydrogen atom, lower alkyl, etc., n represents the integer of 0-3, X < 1> and X < 2> are the same or different, and represent a hydrogen atom, lower alkyl, etc., and a formula (II)n n n n n n n n Is the formula (III)n n n n n n n n [Wherein X..Y..Z represents R 2 C = CR 3 -NR 4 (wherein R 2 , R 3 and R 4 are the same or different and represent a hydrogen atom, lower alkyl, etc.); ], Etc. are provided, a condensed pyrimidine derivative or a pharmacologically acceptable salt thereof. |