abstract |
It is possible to provide stable long-term release and transdermal absorption of hormones (estrogens and / or progestogens) which are active ingredients contained in the pressure-sensitive adhesive layer, and also to provide a hypoallergenic external adhesive to the skin, and to the support layer. As this laminated adhesive, the adhesive layer is 5-50 weight% of a styrene-isoprene-styrene block copolymer, 20-70 weight% of tackifying resin, 10-60 weight% of a softener, and 1-20 weight of polyvinylpyrrolidone. It is an external adhesive which consists of% as an essential component and mix | blends estrogen and / or progestogen as an active ingredient. |