http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20060000320-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G77-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G77-38 |
| filingDate | 2004-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f4bb7a88586bdfb7b572f787383968d |
| publicationDate | 2006-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20060000320-A |
| titleOfInvention | Method for preparing biodegradable polymer-siloxane hybrid body having bioactivity and hybrid body formed therefrom |
| abstract | The present invention provides a method for preparing a biodegradable polymer-siloxane hybrid body having a bioactivity capable of self-generating a bone-like low crystalline apatite layer in a serum or a solution having a similar inorganic ion concentration, and a hybrid body formed therefrom. The present invention relates to a method for producing a biodegradable polymer-siloxane hybrid having a bioactivity of the present invention, comprising: (S1) a biodegradable polymer comprising a functional group having an active hydrogen atom and 3-isocyanatopropyl triethoxysilane Reacting to obtain a coupled polymer; (S2) hydrolyzing and condensing the coupled polymer to synthesize a polymer condensate having silanol groups formed by hydrolysis connected to siloxane bonds; And (S3) binding calcium ions to some of the silanol groups of the polymer condensate. According to the production method of the present invention, a biodegradable polymer-siloxane hybrid having quick and easy bioactivity can be prepared. In addition, when using a biodegradable polymer-siloxane hybrid having a bioactivity formed according to the method of the present invention as a bone defect restoration, the elastic modulus is different from that of a metal material or a ceramic material so that bone absorption occurs. Not only can it be suppressed but also inorganic substances are not eluted to prevent the inflammatory reaction and the problem of exfoliation of the apatite layer, and a low-crystalline carbonate apatite layer is produced on its surface and biodegradability is expressed after a certain period of time. Fully substituted.n n n n Bone defect restoration, biodegradable polymer-siloxane hybrid, bioactive, 3-isocyanatopropyl triethoxysilane, siloxane bond, silanol |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113813930-A |
| priorityDate | 2004-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.