| abstract |
The present invention relates to a method for preparing an optically active ( R ) -2-phenoxypropionic acid derivative, and more particularly, to reacting a p- substituted phenol derivative with an alkyl ( S ) -2-arylsulfonyloxypropionate. The present invention relates to a method of preparing an optically active ( R ) -2-phenoxypropionic acid derivative represented by the following Chemical Formula 1 by using a substance and reacting the alkali metal salt base with a hydrocarbon solvent at a temperature of 60 to 100 ° C.n n n n n n n n n n In Formula 1, A represents a benzoyloxy (BzO) group, an acetoxy (AcO) group, a p- toluenesulfonyloxy ( p- TsO) group, or an aliphatic acyl group of C 1 -C 6 ; R represents a hydrogen atom or an alkyl group of C 1 -C 6 . |