abstract |
The present invention relates to novel pyridazinone derivatives of formula (I) and pharmaceutically acceptable salts and solvates thereof, methods of inhibiting or regulating human immunodeficiency virus (HIV) reverse transcriptase with compounds of formula (I), one or more solvents, carriers Or a pharmaceutical composition comprising a compound of formula (I) in admixture with an excipient, and a process for preparing a compound of formula (I):n n n Formula In n n n n n n n Wherein R 1 to R 4 , R 7 , R 8 and X 1 are as defined in the Summary of the Invention.n n n This compound is useful for treating diseases involving HIV and genetically related viruses. |