http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050116127-A

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filingDate 2003-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef712c2d447b9c054a003da3f05237b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_987b380673a86f56ea87dad0b402d800
publicationDate 2005-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20050116127-A
titleOfInvention Anterior ocular -associated cell sheet, three-dimensional construct and process for producing the same
abstract Providing an anterior eye segment-related cell sheet or three-dimensional structure with little structural defects recovered with cells, desmosome structures between cells, and basal membrane proteins between cells, substrates maintained. Cells are cultured on a cell culture support coated with a surface of a substrate with a temperature responsive polymer having an upper or lower critical dissolution temperature for water of 0 to 80 ° C., followed by multilayering of the cultured cell layer, if necessary.n n n (1) The culture medium temperature is set to the upper limit critical dissolution temperature or the lower limit critical dissolution temperature and, if necessary,n n n (2) adhere the cultured anterior eyepiece-related cell sheet or three-dimensional structure to the polymer membrane,n n n (3) By peeling together with the polymer membrane as it is, an anterior segment-related cell sheet or a three-dimensional structure is produced.
priorityDate 2003-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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