| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0284f0f69e6544d353b77c66dbdf24b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aea5ddac9cae108a5f80101c3f50a351 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2004-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61324068657f75542cf13f15ca8123dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d57c4eb5d7f2fe8d90eb623394478ad1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c656f8a172b2b146ee9a2266bdcdef7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66f929dbf35e98622aaa2e104074f4bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b39509b0faae339767cc1478c4809f34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8a161e2f7780016f68397cfdd776a34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed125c8aa86d1920d76b794e9a780407 |
| publicationDate |
2005-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20050113999-A |
| titleOfInvention |
Novel sp1 decoy oligodeoxynucleotide, pharmaceutical composition comprising the same and method for suppressing the expression of fibrosis factor |
| abstract |
The present invention relates to gene therapy for renal disease, and more particularly, decoy, which can prevent various kidney diseases including fibrosis of the kidneys by using a mechanism of inhibiting the expression of proteins involved in the fibrosis of renal glomeruli and tubular epilepsy. The present invention relates to a compound, a pharmaceutical composition having the same as an active ingredient, and a method for inhibiting the expression of fibrosis-inducing factors by using the decoy compound.n n n The ring-type and phosphorothioated decoy compounds according to the present invention have excellent stability to nucleases and serum and can inhibit transcriptional activation of transcription factors, thereby effectively inhibiting fibrosis. This can prevent progression to chronic renal failure. |
| priorityDate |
2004-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |