| abstract |
The present invention provides a compound that is excellent in accumulation in calcified tissue, ensures rapid urinary excretion and rapid blood clearance, and is useful as a diagnostic or therapeutic agent. In particular, the calcified tissue affinity compound is represented by the formula (AC) a -MC- (LI) b , where MC is the parent nucleus and is an amino group, an amide group, a hydroxy group, a thiol group, a thioether group, a sulfonyl group, a phosphonyl group , Residues of a compound having a plurality of functional groups selected from the group consisting of an aldehyde group, a carboxyl group, a carbonyl group, a halogen and a cyano group; AC is a calcified tissue affinity group; LI is a ligand capable of binding to a metal atom; a is an integer of 1 or more; b is O or an integer of 1 or more. |