| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd7c27b9ec61781656e6f039702fd568 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F26B5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F28F9-0265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F28D7-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F28F9-0253 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D203-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate |
2004-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e13919481b266538e12ba89f31c4f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_671d6d0a31f2fc6a2fa38e8bc7900a3a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eec90cfe6c98d15b0df154b5f968533c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6aa48afe0fe205ba239bc4d3e237f5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fada36aaa19a428337fe698fa84df98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd04d5619448f27700183d1e5eb69bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e7c460a9ecb41256e397a6610b4da4 |
| publicationDate |
2005-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20050103577-A |
| titleOfInvention |
Aziridinecarbonylguanidine derivatives, processes for their preparation and pharmaceutical compositions containing them |
| abstract |
The present invention relates to aziridinecarbonylguanidine derivatives, a preparation method thereof and a pharmaceutical composition comprising the same. The aziridinecarbonylguanidine derivative of the present invention protects cardiomyocytes by enhancing cardiac function recovery and reducing myocardial infarction against ischemia / reperfusion injury through a potent inhibitory action on sodium / hydrogen exchange pathway NHE-1. It is useful for the prevention and treatment of ischemic heart disease such as myocardial infarction, arrhythmia and angina pectoris.It can also be used as a cardioprotective agent during reperfusion therapy such as surgical therapy such as coronary artery bypass surgery, coronary percutaneous plastic surgery, or drug therapy using thrombolytics. have. |
| priorityDate |
2004-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |