http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050092760-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
filingDate | 2004-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e72716d5f67df5446d094e70bf9231a |
publicationDate | 2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20050092760-A |
titleOfInvention | Thienopyrimidinediones and their use in the modulation of autoimmune disease |
abstract | The present invention relates to thienopyrimidinediones of the general formula (1) as well as their pharmaceutically acceptable salts and solvates.n n n <Formula 1>n n n n n n n n Wherein R 1 and R 2 each independently represent C 1-6 alkyl, C 3-6 alkenyl, C 3-5 cycloalkylC 1-3 alkyl or C 3-6 cycloalkyl, each of which Optionally substituted by 1 to 3 halogen atoms,n n n R 3 is a group CO-G or SO 2 -G wherein G is a 5 or 6 membered ring containing a nitrogen atom and a second heteroatom selected from oxygen and sulfur adjacent to nitrogen, said ring being defined herein Substituted by one or more groups,n n n Q is CR 4 R 5 , wherein R 4 is hydrogen, fluorine or C 1-6 alkyl, and R 5 is hydrogen, fluorine or hydroxy,n n n Ar is a 5-10 membered aromatic ring system in which up to 4 ring atoms can be heteroatoms independently selected from nitrogen, oxygen and sulfur, which ring system is optionally substituted by one or more groups as defined herein. Also described are methods of preparing the compounds of the present invention, pharmaceutical compositions containing them and their use in therapy, particularly in the control of autoimmune diseases. |
priorityDate | 2003-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 349.