| abstract |
The present invention relates to a herbal composition having a memory enhancing effect, and more particularly, to a herbal composition consisting of Baekchul, Bokryeong and Sanjoin. The herbal composition of the present invention has an effect of increasing the activation of extracellular-signal regulated kinase (ERK) and cAMP-response element binding protein (CREB) involved in memory formation, and increasing the differentiation and proliferation of neurons. Therefore, the herbal composition of the present invention can be usefully used for the treatment, prevention or amelioration of various diseases and symptoms caused by deactivation of ERK and / or CREB or degeneration of brain cells, in particular, degenerative brain disease and memory loss symptoms. In addition, the herbal composition of the present invention can be applied to food compositions such as health supplements and food additives. |