| abstract |
The present invention provides methods and materials for treating inflammatory diseases. Specifically, the present invention provides polypeptides, isolated nucleic acids, host cells and methods that can be used to induce antibody responses in mammals against antigens such as C5 or C5a. For example, the methods and materials disclosed herein can be used to reduce the effect of C5a in a mammal by reducing the amount of receptor bound total C5a in a mammal. |