abstract |
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. Compounds of formula (I) are useful as antiproliferative agents by inhibiting tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4. In addition, the compounds of formula (I) are useful for the treatment of other diseases associated with signal transduction pathways acting through growth factor receptors.n n n <Formula I> |