abstract |
Provided are compositions and methods for treating a disease associated with compromised vasculostasis. The methods and compositions of the present invention include, for example, strokes, myocardial infarction, cancer, ischemia / reperfusion injury, autoimmune diseases (rheumatic arthritis), ocular diseases (retinopathy or sulfate degeneration or other vitreoretinal disease), inflammatory diseases, vascular It is useful for the treatment of various diseases including leak syndrome, edema, transplant rejection, adult / acute respiratory distress syndrome (ARDS), and the like. |