| abstract |
The present invention relates to a food composition for the prevention and improvement of bone metabolic diseases containing a lump extract as an active ingredient.n n n Oyster extract according to the present invention is the activity to promote the proliferation of osteoblasts, the inhibitory activity of the secretion of bone-absorbing cytokines, the secretion promoting activity of growth factors involved in bone remodeling, the nitric oxide production promoting activity of osteoblasts and osteoclasts It has an activity of inhibiting differentiation, and has an activity of decreasing the concentration of the bone resorption index and inhibiting the decrease of the calcium concentration and the bone density of bone, and thus can be very useful for the prevention or treatment of bone metabolic diseases including osteoporosis. |