http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050050845-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6298c4c8a9dc65a27deeadf713655d9f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2003-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21ef4ca76779f80399acfd1d4c2b3d35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b17099cf2a8ce7edf16e1373186e2c2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcb0d2e9c851ef40a2a2714a13d3353e |
| publicationDate | 2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20050050845-A |
| titleOfInvention | Method of preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using a hydrolytic enzyme |
| abstract | The present invention relates to a method for preparing (S) -indolin-2-carboxylic acid and its methyl ester compound using a hydrolase, and more specifically, racemic indolin-2-carboxylic acid and methanol and chloride Reacting thionyl to obtain a racemic indolin-2-carboxylic acid methyl ester compound; Hydrolyzing the racemic indolin-2-carboxylic acid methyl ester compound using a hydrolytic enzyme to optically divide the racemic indolin-2-carboxylic acid methyl ester compound; And hydrolyzing the optically divided ester compound in an aqueous alkali solution to generate (S) -indolin-2-carboxylic acid. It relates to a process for preparing an acid and a methyl ester compound thereof.n n n The manufacturing method according to the present invention uses (S) -indoline-2-carboxylic acid and its methyl ester having an optical purity of 99% ee or more while simplifying the manufacturing process because of using an inexpensive industrial enzyme having excellent optical purity and yield. It can provide, and because it shows economically greater efficiency than the existing developed process, it is very useful in industry and has the advantage of being practically accessible. |
| priorityDate | 2003-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.