http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050045831-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea0650893830ea9b7b699212d44e6235 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q17-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-68 |
filingDate | 2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec8748be18eb395eba3b4ec3ae6b893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4633fe1c5def7fc50673c1d13715fc34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2147cf7f1509656313b6a6e5548f5e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7986a11d9557fc9e3ea659c960bd058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07574326f00939e1fd763df35cfc64b1 |
publicationDate | 2005-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20050045831-A |
titleOfInvention | Method for preparing phytosphingosine liposome composition |
abstract | The present invention relates to a method for preparing a liposome composition which stabilizes phytosphingosine which is not soluble in water using liposomes to 0.1%, as much as 10%, and a cosmetic composition comprising the liposome composition. Method for producing a phytosphingosine liposome composition according to the present invention, the first step of dissolving phytosphingosine in water and then adding a lactic acid to dissolve the phytosphingosine; A second step of dissolving the phospholipid in a solvent; A third step of mixing the solution prepared in the first step and the solution prepared in the second step; A fourth step of emulsifying the mixture formed in the third step; And a fifth step of extruding the mixture emulsified in the fourth step.n n n The phytosphingosine liposome composition prepared by the method of the present invention can be used in high concentrations in cosmetics while maintaining the inherent functions of phytosphingosine such as antibacterial, anti-inflammatory, and skin regeneration, providing convenience for use, as well as long-term storage or low temperature storage. It is possible to provide a liposome solution having stability that eliminates the leaching of phytosphingosine that may occur. In addition, since the phospholipid used in the present invention is a substance having an effect on moisturizing the skin by forming lamellar, when the liposome composition prepared by the method according to the present invention is used in a cosmetic composition, the effect of strengthening the moisturizing function in addition to the intrinsic function of phytosphingosine There is. In addition, it can be easily applied to water-soluble cosmetic formulations such as skin and essences that have not been used until now due to solubility of phytosphingosine by forming a transparent or semi-transparent solution when diluted in skin formulations, and also used in existing cream products using phytosphingosine powder. It has the advantage of being easy to apply. The phytosphingosine liposomes prepared in the present invention have an advantage that the size of the phytosphingosine is less than 100 nm, and when applied to the skin, it is easy to penetrate into the skin rather than the application form to the epidermis, thereby adding a role as a carrier of phytosphingosine. |
priorityDate | 2003-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.