abstract |
The present invention relates to compounds of formula (I), wherein R is an amino or guanidino group; R 2 is acetyl or trifluoroacetyl; n and q are the same or different and are selected from 0, 1 and 2; X is optionally substituted phenyl, optionally substituted naphthyl or optionally substituted phenyl-Y-optionally substituted phenyl, wherein Y is selected from covalent bonds, CH 2 , CH 2 CH 2 , O and SO 2 ; Provided that when X is phenyl or naphthyl, n and q are both 2 and when X is phenyl-Y-phenyl, where Y is a covalent bond, then n and q are not all 0 Or pharmaceutically acceptable derivatives thereof; Its preparation method; Pharmaceutical formulations containing the above or use thereof in the prevention or treatment of viral infections: |