| abstract |
A quinoxalin-2-one derivative of formula (I) or a pharmaceutically acceptable salt thereof, further comprising an effective amount of a compound that acts as a permeation enhancer or carrier for the quinoxalin-2-one derivative; In addition, pharmaceutical preparations for the administration of a transmembrane or intratympanic membrane, in particular, further comprising a pharmaceutically acceptable solvent if necessary:n n n n n n n n Wherein R 1 and R 2 are each independently hydrogen, methyl-, ethyl-, propyl- or butyl-, or R 1 and R 2 together form a cyclo-alkyl compound,n n n R 3 is methoxy-, ethoxy-, hydroxy-, hydrogen, C 1 -C 4 alkyl- or halogen; And n = 1, 2 or 3. |