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publicationDate 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20050041284-A
titleOfInvention Amlodipine malonate, and process for preparing it
abstract The present invention relates to amlodipine malonate salts and a method for preparing the same, and more particularly, to crystalline acid addition salts prepared by reacting amlodipine and malonic acid, having excellent physicochemical properties such as solubility, stability, non-hygroscopicity, and anti-adhesion properties. The present invention relates to an amlodipine malonate salt represented by the following formula (1), which is effective as a therapeutic agent for cardiovascular diseases including hypertension because of its low toxicity, and a method for preparing the same.
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