abstract |
The present invention relates to amlodipine malonate salts and a method for preparing the same, and more particularly, to crystalline acid addition salts prepared by reacting amlodipine and malonic acid, having excellent physicochemical properties such as solubility, stability, non-hygroscopicity, and anti-adhesion properties. The present invention relates to an amlodipine malonate salt represented by the following formula (1), which is effective as a therapeutic agent for cardiovascular diseases including hypertension because of its low toxicity, and a method for preparing the same. |