| abstract |
The present invention relates to a biomimetic porous composite support composed of nanofibers and microfibers for effectively regenerating damaged tissue and a method of manufacturing the same.n n n The porous composite support of the present invention is a micro-fiber as a basic skeleton, the nanofibers obtained from the physiologically active polymer is composed of a two-dimensional or three-dimensional network form, by using a microfiber has a certain shape and strength biological tissue By allowing nano-fibers to be regenerated in three dimensions, the porosity is improved to increase the surface area associated with cells and provide a structure in which cells adhere and proliferate well. In particular, nanofibers have a feature of increasing tissue regeneration ability by using a polymer that gives physiological activity or a polymer that can increase biocompatibility to existing polymers. |