| abstract |
Bioerodible, biocompatible polymers, injectable depot compositions comprising an amount of solvent, thixotropic agent, and a useful agent effective to plasticize the polymer and to form a gel therewith with a water miscibility of up to 7% at 25 ° C. to provide. The solvent includes aromatic alcohols, esters of aromatic acids, aromatic ketones or mixtures thereof. The composition has significantly improved shear softening properties and reduced infusion, which allows the composition to be easily implanted under the body surface of the patient by injection. |