| abstract |
The 3'-L-valine esters of β-D-2'-C-methylribofuranosyl cytidine provide excellent results for flaviviruses and pestiviruses, including hepatitis C virus. Based on these findings, compounds, compositions for treating flaviviruses, including HCV, optionally comprising administering an effective amount of val-mCyd or a salt, ester, prodrug or ester thereof in a pharmaceutically acceptable carrier , Methods and uses are provided. In another embodiment, val-mCyd is used to treat a virus that replicates via RNA-dependent RNA polymerase. |