http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20050032683-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1af6dbe83b4dd9dc9288569e92777c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 2003-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_024c9c94ed62c0ebb315070dc3dddb07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d17a277112d3b5dfd1569eb0ccb2194 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89cc9dd67e594489963a8620afaefcdc |
| publicationDate | 2005-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20050032683-A |
| titleOfInvention | A process for preparing erdosteine |
| abstract | The present invention relates to a generic name Erdosteine, ie, [(2-oxo-3-tetrahydrothienylcarbamoyl) -methylthio] acetic acid of the formula (I), used as a therapeutic agent for acute and chronic respiratory diseases. A method for preparing the compound, wherein D, L-homocysteine thiolactone hydrochloride of the following formula (II) is reacted with chloroacetyl chloride of the formula (III) to form 3-chloroacetamido-2-oxo- of the following formula (IV) A method for producing erthostein, comprising the steps of preparing tetrahydrothiophene, and reacting a compound of formula (IV) with thioglyconic acid of formula (V) to produce erdostein of formula (I) , The reaction of all the steps is characterized in that by reacting the reactants of each step in a two-phase solution consisting of a basic aqueous solution and an organic solvent for 2 to 3 hours at a temperature of -10 ~ 20 ℃. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220148616-A |
| priorityDate | 2003-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.