abstract |
Compounds of formula (I) are useful as potent and selective antagonists of MIP-1α (CCR3) that bind to MIP-1α receptor CCR1 found on inflammatory cells and immunoregulatory cells (especially leukocytes and lymphocytes).n n n Formula In n n n n n n n Wherein a, b, c, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , Q, W, and Y are as defined above. |