abstract |
The present invention relates to monospecific and multivalent monospecific antibodies and monovalent and multivalent multispecific antibodies. As a preferred example of the antibody, the antibody has one or more identical binding sites, wherein each binding site binds to a target antigen or epitope of the target antigen. As another preferred example, the antibody has two or more binding sites, and these binding sites have affinity for other epitopes or other target antigens of the target antigen or for affinity for the target antigen and heptene. The present invention also relates to a recombinant vector used to express the functional antibody in a host. In more detail, the present invention relates to PAM4 produced as a tumor-associated antibody. The present invention also relates to chimeric PAM4 antibodies and the use of such antibodies in diagnostics and treatment. |